The article deals with the problem of ethical ambiguity of VR Potter’s approaches to the tasks of the civilization development associated with “dangerous knowledge”, primarily to demographic issues. The purpose of the study is to identify the methodological basis for a number of discussion theses in the program book by VR Potter “Bioethics: Bridge to the Futur”. Material of the work is presented by VR Potter’s “Bioethics: Bridge to the Future”. The research was performed using the comparative- historical and cause-and-effect analysis. The paper analyzes the significance of the “dangerous knowledge” considered by VR Potter as part of the humanistic content of bioethics. The author comes to the conclusion that the discussion theses of VR Potter’s bioethical concept are based on the methodological ‘realism’ of an expert who considered the current problems of society in the context of the rationalism of civilization.