ORIGINAL RESEARCH
Ethical assessment of genome editing applications in oncological patients
Pirogov Russian National Research Medical University, Moscow, Russia
Correspondence should be addressed: Victoria O. Abramova
ul. Ostrovityanova, 1, Moscow, 117997, Russia; ur.xednay@ool.ayirotciv
Financing: research by Abramova VO is prepared with financial support from the Russian Science Foundation (project No. 19–18–00422 ‘Socio-humanistic outlines of genomic medicine’)
Author contribution: Abramova VO — analysis of sources, preparing the manuscript draft; Abramova AV — analysis of sources, trial concept, text editing.
- Kuleva SA, Druj AE. Immunologiya i perspektivy` immunoterapii pervichny`x zlokachestvenny`x opuxolej CzNS: adoptivnaya kletochnaya terapiya i viroterapiya. Vo-prosy` onkologii. 2020; 3 (66): 218–222. Russian.
- Rebrikov DV. Redaktirovanie genoma cheloveka. Vestnik RGMU. 2016; (3): 4–15. Russian.
- Jinek M, Chilynksi K, Fonfara I et al. A programmable dualRNA-guided DNA endonuclease in adaptive bacterial immunity. Science. 2012; 337 (6069): 816–821.
- Stadtmauer EA, Fraietta JA, Davis MM, Cohen AD, Weber KL, Lancaster E et al. CRISPR-engineered T cells in patients with refractory cancer. Science. 2020; 367 (6481).
- Grebenshhikova EG, Andreyuk DS, Volchkov PYu, Voronczova MV, Ginter EK, Izhevskaya VL i dr. Redaktirovanie genoma e`mbrionov cheloveka: mezhdisciplinarny`j podxod. Vestnik RAMN. 2021; 76 (1): 86–92. Russian.
- Pticina SN. Primenenie metodov redaktirovaniya genoma i gennoj terapii v lechenii zabolevanij cheloveka. Russkij medicinskij zhurnal. 2021; 29 (10): 57–62. Russian.
- Jonas G. Princip otvetstvennosti. Opy`t e`tiki dlya texnologicheskoj civilizacii. M.: Ajris-press, 2004; 479 s. Russian.
- Yudin BG. Chelovek kak ispy`tuemy`j: antropologiya biomedicinskogo issledovaniya. Lichnost`. Kul`tura. Obshhestvo. 2011; 13: 3 (65–66): 84–96. Russian.
- Dopolnitel`ny`j protokol k Konvencii o pravax cheloveka i biomedicine otnositel`no biomedicinskix issledovanij (Strasburg, 25 yanvarya 2005 g.). Available from: https://base.garant.ru/705 14952/5ac206a89ea76855804609cd950fcaf7/ Russian.
- E`lektronny`j fond pravovoj i normativno-texnicheskoj dokumentacii. Available from: http://docs.cntd.ru/document/901972162 Russian.
- Apresyan RG, Artem`eva OV, Prokof`ev AV. Fenomen moral`noj imperativnosti. M.: IF RAN, 2018; 196 s. Russian.