Financing: The work was performed by the authors at the Federal Budgetary Institution of Science Research Institute of Health and Safety Management of Rospotrebnadzor within the framework of the state assignment ‘Development of methods for molecular genetic diagnostics for quantification of sanogenesis in healthy people’, code of the scientific topic ‘Norma’, number of state registration of research, development work in Unified State Information System for Accounting Research, Development and Technological Works for Civil Use 122030900062–5.

Author contribution: Orlova NV — analysis of scientific data, review of publications related to the topic of the article, making an abstract, writing an article text; Suvorov GN, Gorbunov KS — developing the article design, article editing.