2023 / 02

Следующая статья
DOI: 10.24075/medet.2023.009

ОБЗОР

Этические проблемы проведения фармакотерапии и клинических исследований у пациентов с деменцией

А. С. Казаков, С. К. Зырянов
Информация об авторах

Российский университет дружбы народов (РУДН), Москва, Россия

Для корреспонденции: Сергей Кенсаринович Зырянов
ул. Миклухо-Маклая, д. 6, г. Москва, 117198, Россия; ytisrevinu.ndur@ks_vonayryz

Информация о статье

Вклад авторов: С. К. Зырянов — разработка дизайна статьи, научное консультирование, литературное консультирование; А. С. Казаков — обзор публикаций по теме статьи, составление резюме, написание текста статьи.

Статья получена: 17.04.2023 Статья принята к печати: 20.05.2023 Опубликовано online: 18.05.2023
|
  1. Sperling RA, et al. Toward defining the preclinical stages of Alzheimer’s disease: recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimer’s & Dementia. 2011; 7: 280–292.
  2. Dubois B, et al. Advancing research diagnostic criteria for Alzheimer’s disease: the IWG-2 criteria. Lancet Neurology. 2014; 13: 614–629.
  3. Peter KR, Lynn Beattie B, Feldman HH and Illes J. A conceptual framework and ethics analysis for prevention trials of Alzheimer Disease. Progress in Neurobiology. 2013; 110: 114–123.
  4. Sperling RA, Karlawish J and Johnson KA. Preclinical Alzheimer’s disease — the challenges ahead. Nature Reviews Neurology. 2013; 9: 54–58.
  5. Sperling RA, et al. The A4 study: stopping AD before symptoms begin? Science Translational Medicine. 2014; 6: 228fs13.
  6. Emanuel EJ, Wendler D and Grady C. What makes clinical research ethical? JAMA. 2000; 283: 2701–2711.
  7. Appelbaum PS and Roth LH. Competency to consent to research: a psychiatric overview. Archives of General Psychiatry. 1982; 39: 951–958.
  8. Karlawish JHT, Casarett DJ and James BD. Alzheimer’s disease patients’ and caregivers’ capacity, competency, and reasons to enroll in an early-phase Alzheimer’s disease clinical trial. Journal of the American Geriatrics Society. 2002; 50: 2019–2024.
  9. Kim SYH. Improving medical decisions for incapacitated persons: does focusing on ‘accurate predictions’ lead to an inaccurate picture? Journal of Medicine and Philosophy. 2014; 39: 187–195.
  10. Albert MS, DeKosky ST, Dickson D, Dubois B, Feldman HH, Fox NC, et al. The diagnosis of mild cognitive impairment due to Alzheimer’s disease: recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimer’s Dement. 2011 May; 7(3): 270–279.
  11. Gaster B, et al. Advance directives for dementia: meeting a unique challenge. JAMA. 2017; 318(22): 2175–6.
  12. Cantor NL. On avoiding deep dementia. Hastings Center Report. 2018; 48(4): 15–24.
  13. Dresser R. Advance directives and discrimination against people with dementia. Hastings Center Report. 2018; 48(4): 26–7.