ORIGINAL RESEARCH

Sociocultural aspects of preconception genetic testing

Borisova AO, Nesterov RS
About authors

Pirogov Russian National Research Medical University, Moscow, Russia

Correspondence should be addressed: Aleksandra O. Borisova
ul. Ostrovityanova, d. 1, Moscow, Russia; ur.xednay@avossirob

About paper

Financing: Russian Science Foundation project No. 19-18-00422.

Author contribution: Borisova AO — development of the article concept, preparation of resumes, review of related publications, analysis of scientific data, writing a text; Nesterov RS — review of related publications, selection of empirical data, writing a text.

Received: 2023-05-21 Accepted: 2023-08-28 Published online: 2023-09-14
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Preconception genetic testing for carrier diseases (PGT(C)) became a noticeable sociocultural phenomenon that raised various ethical issues with the individual and society. The issue of informing patients about the risks of giving birth to children with genetic abnormalities includes a range of questions about the probabilistic nature of genetic data, determinism, and cost and quality of medical and genetic counseling. Preventive tasks of genetics inevitably raise a question about the borders of a patient’s autonomy and mutual responsibility of the individual and society. In this article, ethical and philosophical analysis of sociocultural aspects of PGT(C) has been presented, including neoeugenic prevention traits, hubris and genetic fatalism.

Keywords: ethics, preconception genetic testing, medical and genetic counseling, ethical problems of genetics, sociocultural aspects of genetics

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