Author contribution: Shereshneva MV — review of up-to-date and foreign literature regarding the examined issue, formulation of the subject study, determining tasks and goals, laboratory research of induced blood oxidation values, mathematical and statistical treatment of data, making conclusions; Ilyin MV — development of research program, formulation of the subject study, determining tasks and goals, mathematical and statistical treatment of data, and making conclusions.

Compliance with ethical standards: the research underwent through an ethical expertise and was approved by the Ethics Committee of the Yaroslavl Medical University of the Ministry of Health of Russia. Prior to inclusion into research, patients received a detailed explanation of tasks and goals, and a voluntary informed consent was obtained.