2024 / 04

DOI: 10.24075/medet.2024.029
Copyright: © 2024 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).

REVIEW

Neuroethics in medicine. Pressing issues

Filatova YS, Zolotova IA
About authors

Yaroslavl State Medical University, Yaroslavl, Russia

Correspondence should be addressed: Yulia Sergeevna Filatova
Revolutsionnaya St., 5, Yaroslavl, 150000, Russia; ur.liam@avotalif.s.y

About paper

Author contribution: Filatova YS and Zolotova IA made an equal contribution to preparation of the article.

Received: 2024-11-11 Accepted: 2024-12-03 Published online: 2024-12-31
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  1. Shibkova DZ, Bayguzhin PA. Neyronauka: mezhdistsiplinarnaya integratsiya ili ekspansiya? Psikhologiya. Psikhofiziologiya. 2020;3. Available from URL: https://cyberleninka.ru/article/n/neyronauka-mezhdistsiplinarnaya-integratsiya-ili-ekspansiya (accessed: 11.01.2025).
  2. Yoo SH, Choi K, Nam S, Yoon EK, Sohn JW, Oh BM, Shim J, Choi MY. Development of Korea Neuroethics Guidelines. J Korean Med Sci. 2023 Jun 26; 38(25): e193. DOI: 10.3346/jkms.2023.38.e193.
  3. Niebrój LT. Neuroetyka: nowa jakość etyki medycznej? (Neuroethics: new quality of medical ethics?). Ann Acad Med Stetin. 2013; 59(1): 130–6. Polish. PMID: 24734347.
  4. Zimmer AA. Neuroethics Intergration Landscape Report. Global Neuroethics Summit 2020–2021.
  5. O’Shaughnessy MR, Johnson WG, Tournas LN, Rozell CJ, Rommelfanger KS. Neuroethics guidance documents: principles, analysis, and implementation strategies. J Law Biosci. 2023 Oct 26; 10(2): lsad 025. DOI: 10.1093/jlb/lsad025. PMID: 37901886; PMCID: PMC10602660.
  6. Larriviere D, Williams MA, Rizzo M, Bonnie RJ & AAN. Ethics, Law and Humanities Committee, Responding to Requests from Adult Patients for Neuroenhancements: Guidance of the Ethics, Law and Humanities Committee. 73 Neurology. 2009; 1406–1412.
  7. Nuttin B, Wu H, Mayberg H, Hariz M, Gabriëls L, Galert T, et. al. Consensus on guidelines for stereotactic neurosurgery for psychiatric disorders. J Neurol Neurosurg Psychiatry. 2014 Sep; 85(9): 1003–8. DOI: 10.1136/jnnp-2013-306580. Epub 2014 Jan 20. Harlow JM. Passage of an Iron Rod through the Head. Northwest Med Surg J. 1849 Feb-Mar; 1(6): 513–518.
  8. Damasio A. L’errore di Cartesio. Emozione, ragione, cervello umano. Milano: Adelphi; 1994.
  9. Bechara A, Damasio AR, Damasio H, et al. Insensitivity to future consequences following damage to human prefrontal cortex. Cognition. 1994; 50(1–3):7–15. DOI: 10.1016/0010-0277(94)90018-3.
  10. Fumagalli M, Priori A. Functional and clinical neuroanatomy of morality. Brain. 2012; 135(7): 2006–2021. DOI: 10.1093/brain/awr334.
  11. Vicario CM. Emotional Appraisal of Moral Dilemmas: What Neuroimaging Can Tell about the Disgust-Morality Link. J Neurosci. 2016; 36(2): 263–264. DOI: 10.1523/JNEUROSCI.3483-15.2016.
  12. Fumagalli M, Giannicola G, Rosa M, et al. Conflict-dependent dynamic of subthalamic nucleus oscillations during moral decisions. Soc Neurosci. 2011; 6(3): 243–256. DOI: 10.1080/17470919.2010.515148.
  13. Vicario CM, Rafal RD, Borgomaneri S, et al. Pictures of disgusting foods and disgusted facial expressions suppress the tongue motor cortex. Soc Cogn Affect Neurosci. 2017; 12(2): 352–362. DOI: 10.1093/scan/nsw129.
  14. Vicario CM, Martino D. Social communication in Tourette syndrome: a glimpse at the contribution of the insula and the opioid detoxification. Bioelectron Med. 2020; 6:7. DOI: 10.1186/prefrontal cortex. Brain. 2018; 141(8): e58. DOI: 10.1093/brain/ awy140.
  15. Vicario CM, Gulisano M, Maugeri N, et al. Moral Decision-Making in Adolescents with Tourette Syndrome. Mov Disord. 2021; 36(9): 2205–2206. DOI: 10.1002/mds.28705
  16. Vicario CM. Morality and disgust: insights from obsessive compulsive disorder. Front Psychiatry. 2013; 3: 113. DOI: 10.3389/fpsyt.2012.00113.
  17. Pulcu E, Zahn R, Elliott R. The role of self-blaming moral emotions in major depression and their impact on social-economical decision making. Front Psychol. 2013; 4: 310. DOI: 10.3389/fpsyg.2013.00310.
  18. Vicario CM, Lucifora C. Neuroethics: what the study of brain disorders can tell about moral behavior. AIMS Neurosci. 2021 Oct 25; 8(4): 543–547. DOI: 10.3934/Neuroscience.2021029.
  19. Young MJ, Bodien YG, Giacino JT, Fins JJ, Truog RD, Hochberg LR, Edlow BL. The neuroethics of disorders of consciousness: a brief history of evolving ideas. Brain. 2021 Dec 16; 144(11): 3291–3310. DOI: 10.1093/brain/awab290. PMID: 34347037; PMCID: PMC8883802.
  20. Kriegel U. The value of consciousness. Analysis. 2019; 79(3): 503–520.
  21. Hildesheim H, Rogge A, Borzikowsky C, Witt VD, Schäffer E, Berg D. Moral distress among residents in neurology: A pilot study. Neurol Res Pract. 2021; 3(1): 6–9.
  22. Famm K, Litt B, Tracey KJ, Boyden ES, Slaoui M. Drug discovery: a jump-start for electroceuticals. Nature. 2013; 496: 159–161. DOI: 10.1038/496159a.
  23. Qureshi IS, Datta-Chaudhuri T, Tracey KJ, Pavlov VA, Chen ACH. Auricular neural stimulation as a new non-invasive treatment for opioid detoxification. Bioelectron Med. 2020; 6: 7. DOI: 10.1186/ s42234-020-00044-6.
  24. Naqvi NH, Gaznick N, Tranel D, Bechara A. The insula: a critical neural substrate for craving and drug seeking under conflict and risk. Ann N Y Acad Sci. 2014; 1316: 53–70. DOI: 10.1111/ nyas.12415.
  25. Joutsa J, Moussawi K, Siddiqi SH, et al. Brain lesions disrupting addiction map to a common human brain circuit. Nat Med. 2022; 28: 1249–1255. DOI: 10.1038/s41591-022-01834-y.
  26. Lapenta OM, Marques LM, Rego GG, Comfort WE, Boggio PS. tDCS in addiction and impulse control disorders. J Ect. 2018; 34: 182–192. DOI: 10.1097/YCT.0000000000000541.
  27. Zuk P, Lázaro-Muñoz G. DBS and Autonomy: clarifying the role of theoretical neuroethics. Neuroethics. 2021; 14: 83–93. DOI: 10.1007/s12152-019-09417-4.