Author contribution: Khokhlov AL — setting a problem, discussion of key ethical issues, planning and discussion of the article; Chelnokova OG — consultations with patients, study of literature on the topic, systematization and generalization of data, participation in discussion of results, writing and formatting of the article; Skrypnik NV — supervising patients, studying literature on the topic, participating in discussion of the results and writing an article; Dmitrieva AP — studying literature on the topic, participating in discussion of patients and results, and writing an article.

Compliance with ethical standards: meeting of the ethics committee was not held, as the questions to be discussed included practical experience of observing patients in real clinical practice and compliance with ethical standards.