Author contribution: Gayduk AI — collection, systematization and analysis of data from academic literature, text authoring, manuscript formalization; Churakov MV, Polyarnaya N. G., Sineok EV — collection, processing and analysis of socio-d emographic and clinical data; Vlasov YaV — idea, research documentation formalization and registration, manuscript editing and revision, text improvement, final approval of the manuscript for publication.

Compliance with the ethical standards: this study was approved by the Ethics Committee of the Yaroslavl State Medical University of the Ministry of Health of Russia (minutes #21 of February 8, 2018). Each participant signed and submitted the voluntary informed consent form. Adult participants filled out questionnaires voluntarily. The conducted study does not endanger the participants and complies with the biomedical ethics requirements.