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REVIEW

Ethical aspects of clinical trials of blood clotting factors in children with hemophilia

Kudlay DA1,2, Vdovin VV4, Shiller EE5, Khokholov AL6, Davydkin IL7, Borozinets AYu3
About authors

1 I.M. Sechenov First Moscow State Medical University (Sechenov University), Russia, Moscow

2 NRC Institute of Immunology FMBA of Russia

3 AO “GENERIUM”, Russia, Vladimir region, Volginsky

4 Morozovskaya Children’s City Clinical Hospital, Russia, Moscow

5 Odintsovo Regional Hospital of the Moscow region, Russia, Odintsovo

6 Yaroslavl State Medical University, Yaroslavl, Russia

7 Samara State Medical University, Samara, Russia

Correspondence should be addressed: Anton Yu. Borozinets
ul. Testovskaya, d.10, pod. 2, Moscow, 123112, Russia; ur.muireneg@stenizorob.a

About paper

Authors contribution: Kudlay DA — article design development, analysis of scientific material, review of publications on the topic of the article, article editing; Vdovin VV — literary editing of the article, scientific editing of the article; Schiller EE — analysis of scientific material, review of publications on the topic of the article, editing of the article; Khokhlov AL — literary editing; scientific editing of the article; Davydkin IL — literary editing, scientific editing of the article, summary writing; Borozinets AYu — development of article design, analysis of scientific material, review of publications on the topic of the article, compilation of a summary, writing the text of the article, preparation of a list of references.

Received: 2021-10-08 Accepted: 2021-11-24 Published online: 2021-12-30
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Figure. Sequence of clinical trials of new medicinal preparations of blood coagulation factor FVIII in different age groups [16]