ISSN Print 2713-0894
ISSN Online 2713-0908
BIOMEDICAL JOURNAL OF ERMC EASTERN EUROPEAN
Copyright: © 2025 by the authors. Licensee: Pirogov University.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (CC BY).
REVIEW
Pharmacogenetic testing: ethical challenges and solutions
About authors
Yaroslavl State Medical University, Yaroslavl, Russia
Correspondence should be addressed: Svetlana M. Demarina
Revolutsionnaya str., 5, Yaroslavl, 150000, Russia; ur.xednay@msguhc
About paper
Contribution of authors: Demarina SM — selection and analysis of literature, writing the text of the manuscript; Sirotkina AM — literature analysis, editing the manuscript text; Usolkin AA — selection and analysis of literature, writing the text of the manuscript; Dombrovskaya ED — literature analysis, editing of the manuscript text.
Compliance with ethical standards: This work is a review and does not involve human or animal subjects. The approval of the ethics committee was not required.
Received: 2025-12-11
Accepted: 2025-12-18
Published online: 2025-12-27
|
- Sychev DA, Ryzhikova KA, Danilov AV, Grishina EA, Sycheva TV. Pharmacogenetics and pharmacogenomics in Russia: the current state and future prospects. Pharmacogenomics. 2022; 23(4): 233–245.
- Leonova MV, Kutikova GN, Samoylova LP. Strategies and technologies for disseminating and implementing pharmacogenomics in clinical practice: international experience and its potential application in Russia. Pharmacogenetics and Pharmacogenomics. 2024; 1(15): 44–52. Russian.
- Haga SB, LaPointe NMA. The clinical and ethical complexities of pharmacogenetic testing. Current Opinion in Genetics & Development. 2023; 80: 102–108.
- Russian Federation. Federal Law No. 152-FZ of 27 July 2006. On Personal Data (as amended). Collection of Legislation of the Russian Federation. 2006; 31: Art. 3451. Russian.
- Izhevskaya VL, Bochkov NP, Lytkina EA. Informed consent in genetic and genomic testing: regulatory and ethical aspects. Medical Genetics. 2022; 21(5): 3–10. Russian.
- Zakharova NV, Vanyushin IM, Kulpanova EA. International experience in psychopharmacogenetics: ethical and legal aspects. Lex Genomica. 2024; 2(8): 15–24. Russian.
- Nuffield Council on Bioethics. Pharmacogenetics: ethical issues. London: Nuffield Council on Bioethics. 2023; 186 p.
- Dromics Labs Research Team. The ethical, legal and social implications of pharmacogenomics: a critical review. Journal of Bioethical Inquiry. 2024; 21(1): 45–58.
- Joly Y, Brisson J, Knoppers BM. Genetic discrimination in the quantitative era. American Journal of Human Genetics. 2021; 108(10): 1807–1814.
- Mokhov AA, Yavorsky AN. Genetic technologies and law: current issues and development prospects. Courier of Kutafin Moscow State Law University (MSAL). 2020; 5(45): 34–42. Russian.
- Sabatello M, Chen Y, Saks JF, Richardson HS. Precision medicine and social justice: addressing health inequities. American Journal of Bioethics. 2023; 23(7): 9–12.
- Wieschowski S, Delgado A, Schicktanz S, Ballantyne A, Coveney AP, Eichinger T, Essén K, Franke U, Geerligs L, Hens K, Huys I, Mahr D, Müller T, Nacci F, Proverbio D, Richter G, Sleeboom-Faulkner M, Taibi R, Tomljenovic H. Bioethical challenges in pharmacogenomics: a systematic review of the literature. Frontiers in Genetics. 2022; 13: 924–931.